The appropriate chromosomes are needed with the ability to combine them with those of the sperm to transform an egg into a healthy embryo. It needs to have enough energy to be able to grow and divide normally.
Poor-quality eggs can lead to chromosomally abnormal pregnancies and the risk of babies with genetic disorders.
The age of women is the main factor which influences the quality of the eggs. Quality and quantity of eggs begins to reduce after the age of 35 and at age 40 poor quality outnumbers good quality, decreasing the chances of a successful pregnancy.
In addition to the age factor, poor quality eggs in younger women may be caused by:
During each cycle a certain number of follicles, known as the ovarian reserve, are recruited and expel their eggs but over the years they become exhausted and lead to the menopause. To assess and quantify the ovarian reserve, thuis is done by:
Currently, there is no analytical or other non-invasive technique to indicate that a woman’s eggs, even though they have a high number, are of good quality. Therefore the best way to check if the begs can develop correctly is with an IN VITRO FERTILISATION (IVF) CYCLE.
This allows us to observe any mutations in the genes that encode the proteins of the outer layer which becomes more rigid and difficult to fertilise. An Intracytoplasmic sperm injection, ICSI, would be a solution to this alteration.
Of course there are also a number of described mutations that make the egg unable to be fertilized or that once fertilized does not divide properly.
IVF and pre-implantation genetic diagnosis (PGD), help detect chromosomal and genetic abnormalities in the embryo, chromosomal errors cannot be avoided but can be diagnosed.
PGD allows only embryos free of genetic and chromosomal abnormalities to be transferred to the maternal uterus, so transferring only normal embryos maximizes the chances of implantation, pregnancy, and a healthy baby.
There is no treatment to improve egg quality, but some recommendations can be made in certain cases such as:
At HC Fertility each couple is recommended to improve life styles, according to their case and together with personalized stimulation, they can optimize the cycle and obtain best results.
WE MAKE IT POSSIBLE
At HC Fertility we have been verifying for many years that, for our patients, a complete diagnosis in time is undoubtedly the best option to be able to assess and find solutions according to each case.
In our centre, in addition to our consultations, operating rooms, Andrology, Cryobiology and IVF laboratory, we have our own clinical analysis laboratory, so we can offer safety, comfort and speed to carry out this diagnosis and be able to assess your results with the gynaecologist on the same day.