The associated hyperuricemia is due to an overproduction or an under excretion of uric acid.
Gout can also have a heritable component which is related to acquire causes of "hyperuricemia":
Alcohol ingestion in any form promotes hyperuricemia by increasing urate production and decreasing the renal excretion of uric acid.
90% of patients with primary gout are male who are usually over 30 years of age, in female the onset of Gout is predominantly postmenopausal.
Uric Acid Kidney Stones are present in 5 - 10% of patients with Gout Arthritis and this can increase to 50% if the level of Uric Acid is above 13mg/Dl.
Symptoms of Gout are characterized by the sudden onset of pain which can be frequently nocturnal either with or without apparent cause.
Gout can come on following a rapid fluctuation in serum rate levels such as alcohol excess of medication changes.
The matatarsophalageal joint of the big toe is the most susceptible joint to suffer on the foot although in general the feet, ankles and knees are commonly affected.
One or more joints can be affected at the same time on any one attack. The involved joints are swollen and are excruciatingly tender often with a heat sensation and redness to the skin.
A symptomatic periods of months and even years can commonly follow the initial attack so it becomes very important to have the initial diagnosing of the condition and then the management of it between attacks during the "symptoms-free time".
Guidelines for Lifestyle.
The Diet - High Purine foods include all meats - sea food - meat extracts and gravy - yeast & yeast extracts - beans - peas - lentils - oatmeal - spinach - asparagus - cauliflower - mushrooms. These foods should be restricted to low-normal quantities in patients suffering from gout.
Alcohol - all alcoholic drinks can input to gout conditions, especially beers and high volume alcoholic drinks.
Hyperaemic medication - Some diuretics and low dosage aspirin or Nialin can induce Gout attack.
If identified early on and kept under medical surveillance, the prognosis can be positive together with a controlled diet. Gout can develop into chronic deforming arthritis so it is extremely important to check the serum level of the blood regularly and foillow the doctors instructions and advice. We can say that this disease is not life threatening but its consequences can be vary painful and fastidious and can develop to be an extremely severe disease especially if the kidneys is involved through the metabolism. If you think you may suffer from Gout go to see your doctor for advice.